20% Albumin

How it works

Benefits

Risks & contraindications

Evidence quality

Highlighted claims

• Albumin is the main binding and transport protein in plasma and the principal determinant of vascular oncotic pressure. — Efficacy of intraoperative use of 20% albumin in combination with Ringer’s lactate versus Ringer’s lactate during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: protocol for a randomised controlled, open-label clinical trial (ALBUCHIP trial)
• The article states that albumin efficacy in major non-cardiac surgery with high fluid requirements has not been sufficiently evaluated. — Efficacy of intraoperative use of 20% albumin in combination with Ringer’s lactate versus Ringer’s lactate during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: protocol for a randomised controlled, open-label clinical trial (ALBUCHIP trial)
• Known risks of 20% human albumin include rare immunoallergic reactions, infrequent cardiovascular events, and possible renal impairment. — Efficacy of intraoperative use of 20% albumin in combination with Ringer’s lactate versus Ringer’s lactate during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: protocol for a randomised controlled, open-label clinical trial (ALBUCHIP trial)
• A 20% albumin solution may reduce the total crystalloid volume needed during high-fluid-demand surgery. — Efficacy of intraoperative use of 20% albumin in combination with Ringer’s lactate versus Ringer’s lactate during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: protocol for a randomised controlled, open-label clinical trial (ALBUCHIP trial)