Abnormal BUN-to-Creatinine Ratios

How it works

Risks & contraindications

Highlighted claims

• A low BUN-to-creatinine ratio can occur through decreased BUN, increased creatinine, or both. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Dehydration can concentrate BUN and creatinine while reducing renal clearance capacity. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Liver disease can reduce BUN independently of kidney function by disrupting urea synthesis from ammonia. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• An elevated BUN-to-creatinine ratio can reflect impaired kidney function, reduced GFR, or glomerular damage. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Low protein intake can lower BUN by reducing urea production. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Congestive heart failure can raise the ratio by reducing cardiac output and renal perfusion. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Pregnancy can lower the ratio through dilution from increased blood volume and fluid retention. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation
• Severe gastrointestinal bleeds can raise BUN while reducing renal perfusion. — BUN-to-Creatinine Ratio: Renal Physiology, Lab Methods, and Clinical Interpretation