Anticoagulant Drug Interactions

Risks & contraindications

Interactions

Comparisons

Evidence quality

Highlighted claims

• Anticoagulants prevent thromboembolic events but increase internal bleeding risk, especially gastrointestinal bleeding. — Barriers and facilitators to implementing a shared decision-making tool for anticoagulant-related drug–drug interactions: a qualitative study across three academic medical centres in the USA
• Bleeding risk increases when anticoagulants are combined with medications such as NSAIDs or SSRIs. — Barriers and facilitators to implementing a shared decision-making tool for anticoagulant-related drug–drug interactions: a qualitative study across three academic medical centres in the USA
• Population-level bleeding estimates often lack enough patient-level detail for individualized clinical decisions. — Barriers and facilitators to implementing a shared decision-making tool for anticoagulant-related drug–drug interactions: a qualitative study across three academic medical centres in the USA
• Most existing anticoagulant drug interaction interventions rely on passive alerts or backend monitoring systems. — Barriers and facilitators to implementing a shared decision-making tool for anticoagulant-related drug–drug interactions: a qualitative study across three academic medical centres in the USA
• Between about 4% and 7% of patients receiving oral anticoagulants are prescribed NSAIDs at a given time. — Barriers and facilitators to implementing a shared decision-making tool for anticoagulant-related drug–drug interactions: a qualitative study across three academic medical centres in the USA