Antiemetic Therapy

Uses

Dosage & preparation

Evidence quality

Highlighted claims

• Guidelines for highly emetogenic chemotherapy recommend standard combinations of three or four drugs including dexamethasone, a 5-HT3 receptor antagonist, an NK1 receptor antagonist, and sometimes olanzapine. — Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial
• Despite four-drug antiemetic combinations, nausea control remains limited. — Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial
• Dexamethasone is permitted for enrolled participants because it is necessary for anticancer drugs with high emetogenic risk. — Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial
• Olanzapine use is at the treating physician's discretion and will be included as a covariate to account for potential confounding. — Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial