CAR-Treg Cells
Cross-source consensus on CAR-Treg Cells from 1 sources and 4 claims.
1 sources · 4 claims
How it works
Benefits
Evidence quality
Highlighted claims
- CAR-Treg approaches aim to restore immune tolerance rather than deplete cells. — Resetting autoimmune disease with CAR cell therapies
- Tregs can integrate native and CAR-mediated co-stimulatory signals to suppress allograft rejection. — Resetting autoimmune disease with CAR cell therapies
- CD19-targeted CAR-Tregs restored immune homeostasis in a murine SLE model. — Resetting autoimmune disease with CAR cell therapies
- First-in-human CAR-Treg data in autoimmunity came from an interim phase 1 study in refractory rheumatoid arthritis. — Resetting autoimmune disease with CAR cell therapies