ChangePDD Trial

Uses

Comparisons

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Other

Highlighted claims

• The ChangePDD trial compares CBASP with behavioural activation in adults with treatment-resistant persistent depressive disorder. — Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled changePDD trial
• The trial is a prospective, multicentre, rater-blinded randomised controlled trial with a parallel-group design and active control group. — Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled changePDD trial
• The trial tests whether CBASP is superior to BA in reducing depressive symptoms over a 16-week multimodal programme. — Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled changePDD trial
• The target randomised sample size is 396 participants after screening about 1,000 adults. — Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled changePDD trial
• The trial includes a 48-week post-treatment follow-up and health-economic cost-benefit analyses. — Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled changePDD trial