Chloride-rich fluids

Uses

How it works

Evidence quality

Where it comes from

Highlighted claims

• The study cannot fully separate chloride or sodium toxicity from illness severity, fluid volume, or the reasons for greater saline exposure. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• Normal saline is widely used in critically ill patients as a resuscitation fluid, maintenance fluid, and drug solvent. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• The study notes that chloride-rich fluids can cause iatrogenic hyperchloraemia, particularly with large short-term saline exposure. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• Rapid infusion of large saline volumes can raise chloride levels and may contribute to several adverse physiological effects. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• The findings support caution with chloride-rich solutions and consideration of balanced or non-chloride-based fluids when appropriate. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital