Chronic Neuropathic Pain

How it works

Evidence quality

Highlighted claims

• Chronic neuropathic pain at 3 months is a secondary outcome measured with the DN4 questionnaire, an assessment that prior thoracic lidocaine studies have not systematically included. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• The trial's assessment of chronic neuropathic pain is limited because DN4 is used alone without concurrent measures of long-term pain intensity or functional interference. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• Intravenous lidocaine is hypothesised to reduce the transition from acute postoperative pain to chronic neuropathic pain by attenuating neuroinflammation and central sensitisation. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial