Confounding factors

Interactions

Evidence quality

Highlighted claims

• Diarrhoea, vomiting, high-dose diuretics, renal replacement therapy, nasogastric drainage, heart failure, and intracranial hypertension may affect chloride balance. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• The study could not systematically assess several chloride-influencing factors because transferred patients had missing or inconsistent data. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• Several clinical conditions and interventions can alter blood chloride levels. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• Chronic kidney disease and chronic lung disease may influence electrolyte and acid-base balance. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital
• The hyperchloraemic group may have included sicker patients or patients receiving different management despite similar APACHE II scores. — Impact of ICU-acquired hyperchloraemia on all-cause in-hospital mortality in adult patients who were critically ill: a retrospective cohort study in a tertiary grade A hospital