CSF-STREAM

Uses

Preparation

Comparisons

Evidence quality

Highlighted claims

• CSF-STREAM is used as an exploratory non-invasive 7-Tesla MRI technique to assess glymphatic-system activity. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial
• CSF-STREAM metrics are measured at baseline, month 3, and month 6. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial
• CSF-STREAM quantitative metrics include CSF mobility, principal orientation of CSF mobility, and fractional anisotropy. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial
• The optimal time to measure CSF mobility with CSF-STREAM is unknown. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial
• CSF motion is probed in multiple subarachnoid, ventricular, cortical, basal ganglia, and perivascular regions. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial
• Ultra-high-field 7-Tesla MRI permits CSF-STREAM assessment of glymphatic-related CSF mobility that cannot be performed on 3-Tesla MRI. — Stimulating amyloid-β clearance in cerebral amyloid angiopathy with low-sodium oxybate and/or non-invasive vagus nerve stimulation (Clear-Brain): study protocol for a randomised pre-post trial