Cumulative Incidence

Uses

How it works

Comparisons

Highlighted claims

• The target includes cumulative disease incidence that would have been observed for an investigational vaccine in the target population. — Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data
• Task III estimates cause-specific cumulative incidence curves and overall cumulative incidence when multiple serotypes co-circulate. — Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data
• The framework extends surrogate-index and data-fusion methods to survival endpoints with right-censoring and competing risks. — Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data
• With right-censoring, the weighting formula uses inverse probability of censoring weights. — Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data
• Time-to-clinical-endpoint outcomes remain common primary endpoints in vaccine trials. — Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data