Diagnostic Comparators
Cross-source consensus on Diagnostic Comparators from 1 sources and 5 claims.
1 sources · 5 claims
Risks & contraindications
Comparisons
Other
Highlighted claims
- PCR will be treated as a comparator rather than the reference standard when it uses validated primers for M. leprae-specific genomic sequences. — Sensitivity of immunohistochemistry in the laboratory diagnosis of leprosy: a systematic review protocol
- Anti-PGL-1 serology, including NDO-BSA assays, will be used only as a comparator and not as a gold standard. — Sensitivity of immunohistochemistry in the laboratory diagnosis of leprosy: a systematic review protocol
- The accepted primary PCR target is the RLEP repetitive element because of its high genomic copy number and superior analytical sensitivity. — Sensitivity of immunohistochemistry in the laboratory diagnosis of leprosy: a systematic review protocol
- Conventional PCR-RLEP and qPCR-RLEP will both be accepted, but sensitivity estimates will be calculated separately. — Sensitivity of immunohistochemistry in the laboratory diagnosis of leprosy: a systematic review protocol
- Anti-PGL-1 antibody titres may reflect past exposure rather than active disease, and diagnostic cutoffs vary across studies. — Sensitivity of immunohistochemistry in the laboratory diagnosis of leprosy: a systematic review protocol