EASE-SIB Trial
Cross-source consensus on EASE-SIB Trial from 1 sources and 6 claims.
1 sources · 6 claims
Uses
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Highlighted claims
- The EASE-SIB trial is designed to test the effectiveness of nucleus accumbens DBS for severe refractory SIB in children with profound autism. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial
- The trial is a single-centre randomized double-blinded crossover study at the Hospital for Sick Children in Toronto. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial
- The planned enrolment is 25 participants with autism spectrum disorder and severe refractory SIB. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial
- All participants receive bilateral DBS electrode implantation targeting the nucleus accumbens. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial
- Participants are randomized after recovery to ON-then-OFF or OFF-then-ON stimulation sequences. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial
- Each randomized trial block lasts 12 weeks and the blocks are separated by a 2-week washout period. — Electrical Stimulation of the Nucleus Accumbens for Severe, Refractory Self-Injurious Behaviour in Children (EASE-SIB): protocol for a randomised double-blinded crossover trial