eIF2α Phosphorylation
Cross-source consensus on eIF2α Phosphorylation from 1 sources and 4 claims.
1 sources · 4 claims
How it works
Highlighted claims
- eIF2α phosphorylation is described as a core mechanism of the integrated stress response. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- Phosphorylated eIF2α inhibits eIF2B and reduces ternary complex formation. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- PERK, PKR, HRI, and GCN2 respond to distinct stress inputs that converge on eIF2α phosphorylation. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- eIF2α phosphorylation represses most translation but favors translation of regulatory mRNAs such as ATF4. — Stress-induced Eukaryotic Translational Regulatory Mechanisms