Emergency and Critical Care Research

How it works

Risks & contraindications

Comparisons

Evidence quality

Highlighted claims

• The two eligible trials included in the ENHANCE survey were PRONTO (procalcitonin-supported sepsis assessment) and UK-ROX (conservative vs usual oxygen therapy). — Enhancing communication with bereaved relatives about emergency and critical care trials (ENHANCE): a mixed-methods study
• Emergency and critical care research is essential for improving treatment but faces major consent challenges due to patient incapacity and time-critical interventions. — Enhancing communication with bereaved relatives about emergency and critical care trials (ENHANCE): a mixed-methods study
• Excluding the sickest patients from research trials would introduce bias and weaken study validity. — Enhancing communication with bereaved relatives about emergency and critical care trials (ENHANCE): a mixed-methods study
• Most emergency and critical care research protocols currently lack a clear pathway for informing bereaved relatives when a patient took part before death. — Enhancing communication with bereaved relatives about emergency and critical care trials (ENHANCE): a mixed-methods study
• ENHANCE findings align with paediatric emergency research, where professionals initially feared negative parental reactions but found responses were often positive when lack of prior consent was clearly explained. — Enhancing communication with bereaved relatives about emergency and critical care trials (ENHANCE): a mixed-methods study