Esketamine

Uses

Benefits

Comparisons

Evidence quality

Highlighted claims

• No randomised controlled trial has yet evaluated esketamine specifically for haematologic-oncologic procedures in children. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Esketamine offers approximately twice the potency of racemic ketamine with less cardiorespiratory depression and a lower incidence of psychotropic side effects. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Prior use of esketamine as an adjunct in same-visit bidirectional endoscopy achieved a 61% reduction in desaturation and hypotension versus control. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Esketamine has been studied as a propofol adjunct across multiple paediatric procedural contexts including 3-Tesla MRI, hydrostatic reduction of intussusception, and forearm fracture management. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• In ERCP procedures, esketamine as a propofol adjunct reduced the required propofol dose without affecting recovery time or patient satisfaction. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol