Estrobolome
Cross-source consensus on Estrobolome from 1 sources and 5 claims.
1 sources · 5 claims
How it works
Highlighted claims
- The estrobolome is the community of gut microbiota that metabolizes estrogens, and estrogen loss during menopause causes dramatic loss of gut microbiome diversity. — Menopause, the Gut-Estrogen Axis, and Methylation: A Clinical Guide
- Declining estradiol degrades tight junction integrity, increasing intestinal permeability and fueling systemic chronic inflammation. — Menopause, the Gut-Estrogen Axis, and Methylation: A Clinical Guide
- Reduced ER Alpha activity from estrogen decline suppresses GLP-1 production, which is itself a primary mediator of tight junction integrity, creating a self-reinforcing inflammatory loop. — Menopause, the Gut-Estrogen Axis, and Methylation: A Clinical Guide
- Estrogen loss shifts the gut microbiome from a female-patterned community toward an androgenic profile associated with male physiology. — Menopause, the Gut-Estrogen Axis, and Methylation: A Clinical Guide
- The androgenic microbiome shift directly drives visceral fat accumulation preferentially over hips, thighs, and gluteal tissue. — Menopause, the Gut-Estrogen Axis, and Methylation: A Clinical Guide