Ex Vivo Granuloma Model
Cross-source consensus on Ex Vivo Granuloma Model from 1 sources and 4 claims.
1 sources · 4 claims
How it works
Preparation
Comparisons
Evidence quality
Highlighted claims
- Freshly isolated PBMCs are incubated for seven days with Mycobacterium tuberculosis-derived antigen on PPD-coated beads or albumin-coated controls. — Molecular characterisation of progressive pulmonary sarcoidosis: protocol for a longitudinal multi-centre study to develop peripheral blood circulating biomarkers for predicting pulmonary sarcoidosis progression
- By day seven, PBMCs from sarcoidosis patients form structured granuloma-like aggregates. — Molecular characterisation of progressive pulmonary sarcoidosis: protocol for a longitudinal multi-centre study to develop peripheral blood circulating biomarkers for predicting pulmonary sarcoidosis progression
- The granuloma model compares transcriptional programmes and protein interaction networks between progressive and non-progressive sarcoidosis. — Molecular characterisation of progressive pulmonary sarcoidosis: protocol for a longitudinal multi-centre study to develop peripheral blood circulating biomarkers for predicting pulmonary sarcoidosis progression
- The ex vivo granuloma aim is powered with 20 progressive and 20 non-progressive cases. — Molecular characterisation of progressive pulmonary sarcoidosis: protocol for a longitudinal multi-centre study to develop peripheral blood circulating biomarkers for predicting pulmonary sarcoidosis progression