Hip Fractures in Elderly Patients

How it works

Evidence quality

Highlighted claims

• Advanced age, trauma, and prolonged immobility are the major contributors to DVT risk in hip-fracture patients. — Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol
• The trial results may not apply to patients with severe underlying disease (ASA 4–5) or moderate to severe cognitive impairment (MMSE ≤20), as these groups are excluded. — Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol
• Age-related loss of vascular wall elasticity, endothelial injury from trauma, coagulation activation, and reduced lower-limb venous return all contribute to thrombosis risk in this population. — Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol
• Severe hip-fracture pain is typically greatest immediately after the fracture rather than after surgery. — Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol
• The first 24 hours after hip fracture may be the peak period for pain-related stress response and thrombotic pathophysiology, which is why patients admitted more than 24 hours after injury are excluded from the trial. — Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol