Hormone Replacement Therapy

How it works

Benefits

Preparation

Comparisons

Evidence quality

Highlighted claims

• The article rejects oral contraceptives as a substitute for hormone restoration in perimenopausal women unless contraception is needed. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The article distinguishes MHT as symptom management and HRT as restoration to physiologic hormone levels. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The timing hypothesis states that hormone therapy started early in the menopausal transition provides more protective benefit than therapy started late after damage accumulates. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• Oral micronized progesterone is preferred over cream for most women because of better central nervous system effects. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The article argues that ideal hormone replacement should mimic cyclic rhythm rather than only produce static average hormone levels. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The article says HRT aims at bone protection, vascular health, cognitive preservation, and metabolic regulation. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The article says transdermal creams, injections, patches, and oral estradiol are possible estradiol delivery methods, with oral estradiol less preferred because of first-pass liver metabolism. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health
• The article argues that the Women's Health Initiative used the wrong population, wrong hormones, and wrong timing for judging bioidentical hormone restoration. — The Great Menopause Myth: Perimenopause, HRT, Nutrition, and Metabolic Health