Hormones

Uses

How it works

Dosage & preparation

Risks & contraindications

Comparisons

Evidence quality

Highlighted claims

• Women are disproportionately affected by migraines, and hormonal cycling is a direct reason. — Functional Medicine Approach to Migraines: Root Causes and Prevention
• The most common hormonal migraine pattern is migraines in the days immediately before menstruation, when estrogen drops sharply. — Functional Medicine Approach to Migraines: Root Causes and Prevention
• Estrogen regulates serotonin, exerts anti-inflammatory effects in the brain, and influences nervous system sensitivity, so its decline increases migraine vulnerability. — Functional Medicine Approach to Migraines: Root Causes and Prevention
• The key hormonal factor in migraines is estrogen fluctuation and instability, not absolute estrogen level. — Functional Medicine Approach to Migraines: Root Causes and Prevention
• Tracking menstrual cycles to map migraine patterns is one of the most actionable diagnostic tools available to women. — Functional Medicine Approach to Migraines: Root Causes and Prevention
• Estrogen and related hormones are pervasive in the brain, and their fluctuation during perimenopause directly alters mood, anxiety, sleep, concentration, and moment-to-moment self-perception. — Emotional Health in Perimenopause: Trauma, Shame, and Resilience
• Dietary fat supplies the raw material for building and maintaining all cell membranes throughout the body. — Six Benefits of a High-Fat Diet
• Critical hormones including cortisol, testosterone, and estrogen require dietary fat as their precursor. — Six Benefits of a High-Fat Diet
• Menopause involves declining progesterone levels that frequently cause depression. — Progesterone and Depression: Hormonal Imbalance Recovery
• Perimenopausal hormone levels can swing dramatically cycle to cycle, making a single blood test an unreliable measure of hormonal trajectory. — Longevity and Healthspan by Decade: A Clinical Roadmap