HUA–HTN Comorbidity

Risks & contraindications

Evidence quality

Other

Highlighted claims

• When HUA and HTN co-occur, their combined cardiovascular and cerebrovascular harm exceeds the sum of either condition acting alone. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis
• The HUA+HTN comorbidity markedly elevates risk of stroke, ischaemic heart disease, myocardial hypertrophy, and left ventricular diastolic dysfunction. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis
• Existing research on HUA+HTN comorbidity in Chinese children and adolescents is limited by regional constraints, small sample sizes, inconsistent age stratification, and incompatible diagnostic criteria. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis
• In adolescent populations, the comorbidity can cause subclinical damage including microangiopathy, premature arteriosclerosis, and declined glomerular filtration function, raising the probability of adult chronic cardiorenal disease. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis
• Cardiovascular diseases arising in childhood or adolescence frequently persist into adulthood, making the current paediatric comorbidity burden a long-term public health concern. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis
• Both HUA and HTN are trending toward younger onset in mainland China at a rate faster than the global trend. — Risk factors for hyperuricaemia–hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis