Human-Mouse Comparison

How it works

Comparisons

Highlighted claims

• Human ncRNA length was reported as 650,012,775 bp, compared with 243,294,640 bp in mouse. — Noncoding RNAs evolutionarily extend animal lifespan
• Humans had more ncRNA genes than mice, whereas mice had more protein-coding genes than humans. — Noncoding RNAs evolutionarily extend animal lifespan
• Human noncoding regions contained more GGTGCG and CGTATA than mouse noncoding regions, while mouse noncoding regions contained more TCTCTC. — Noncoding RNAs evolutionarily extend animal lifespan
• Protein-coding length differed less strongly between humans and mice than ncRNA length did. — Noncoding RNAs evolutionarily extend animal lifespan
• The study used humans and mice as a focused evolutionary contrast because their lifespans differ substantially. — Noncoding RNAs evolutionarily extend animal lifespan
• The paper argues that human lifespan evolution involved accumulation of long-life motifs and reduction of short-life motifs. — Noncoding RNAs evolutionarily extend animal lifespan