Hydrochlorothiazide
Cross-source consensus on Hydrochlorothiazide from 1 sources and 5 claims.
1 sources · 5 claims
Risks & contraindications
Comparisons
Highlighted claims
- HCTZ-induced hypokalemia causes muscular weakness and, in cardiac patients, directly increases arrhythmia risk. — Eight Medications Doctors Fear Most
- HCTZ's continuous diuretic effect regardless of fluid status can cause profound dehydration when layered on top of an intercurrent illness. — Eight Medications Doctors Fear Most
- HCTZ-induced hyponatremia is particularly dangerous in older women, potentially causing confusion, seizures, and requiring slow hospital correction. — Eight Medications Doctors Fear Most
- Overly rapid correction of HCTZ-induced hyponatremia can cause central pontine myelinolysis, a dangerous swelling of the brainstem. — Eight Medications Doctors Fear Most
- ACE inhibitors, beta-blockers, calcium channel blockers, and ARBs are all preferred over HCTZ for initial antihypertensive therapy. — Eight Medications Doctors Fear Most