Immune Pathways

How it works

Highlighted claims

• The literature review identified immune components mainly stimulated by the immunomodulators associated with atrial fibrillation reporting. — Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review
• The review identified another cluster of immune components that was predominantly inhibited by the implicated immunomodulators. — Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review
• The study proposed an immune model in which immune activation contributes to electrical and structural atrial remodeling. — Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review
• Macrophages may contribute to atrial fibrillation through mechanisms involving IL-1 beta, IL-6, TGF beta, fibroblast proliferation, connexin inhibition, fibrosis, and disturbed conduction. — Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review
• NK cells, macrophages, and Th1 cells may form a self-reinforcing inflammatory loop contributing to the progression of atrial fibrillation. — Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review