Intravenous Lidocaine

Uses

How it works

Benefits

Risks & contraindications

Comparisons

Highlighted claims

• Signs of systemic lidocaine toxicity that require immediate infusion cessation include ECG irregularities, drowsiness, metallic taste, perioral numbness, tinnitus, and seizure activity. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• A 20% lipid emulsion is kept available as a rescue treatment for severe local anaesthetic systemic toxicity. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• Continuous ECG monitoring is required throughout the postoperative lidocaine infusion period. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• Intravenous lidocaine has multimodal analgesic, antihyperalgesic, and anti-inflammatory actions that make it a candidate for perioperative use. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• In the trial protocol, both groups receive the same bolus and intraoperative lidocaine infusion; only the postoperative infusion differs, with the control group receiving normal saline. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• The proposed mechanisms of intravenous lidocaine include sodium-channel blockade, suppression of proinflammatory cytokines, and modulation of central sensitisation. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial
• Intravenous lidocaine may reduce acute nociceptive input, opioid requirements, neuroinflammation, and the transition to chronic neuropathic pain. — Efficacy of perioperative intravenous lidocaine infusion on postoperative recovery and analgesia in patients undergoing video-assisted thoracoscopic surgery: study protocol for a randomised, double-blind, placebo-controlled trial