IOC2

Uses

How it works

Benefits

Dosage & preparation

Evidence quality

Highlighted claims

• The IOC2-guided trial arm titrates remifentanil to maintain IOC2 between 35 and 45. — Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial
• IOC2 is the trial intervention's nociceptive sensitivity index used to guide intraoperative analgesia. — Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial
• IOC2 is calculated from EEG and frontal electromyography signals and estimates movement probability in response to noxious stimulation. — Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial
• The trial hypothesises that IOC2 monitoring will reduce opioid consumption in ovarian cancer patients after neoadjuvant chemotherapy. — Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial
• A cited prior study suggested that maintaining IOC2 at 35-45 may reduce endocrine suppression and support postoperative recovery. — Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial