Laboratory and Statistical Methods
Cross-source consensus on Laboratory and Statistical Methods from 1 sources and 6 claims.
1 sources · 6 claims
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- Participants self-collect three vaginal swabs two to three days after each menstruation. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland
- The primary analysis compares pooled tampon and cup periods with pad periods using a mixed-effects linear regression model. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland
- Harmonised processing across all three countries is intended to reduce inter-site methodological variability. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland
- Extracted DNA is sent to the Arora Lab for bacterial load quantification, amplification, and 16S rRNA gene amplicon sequencing. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland
- The 300-participant target includes a buffer for expected attrition of 10% in the second crossover period and 20% in the third. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland
- Microbial profiling uses 16S rRNA sequencing from SMART-eNAT swabs. — Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18–35 years in Cameroon, Peru and Switzerland