Local Field Potentials

Uses

How it works

Evidence quality

Other

Highlighted claims

• The study evaluates whether chronically recorded GPi LFPs can guide DBS programming in dystonia. — Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol
• The primary outcome assesses reproducibility of low-frequency alpha-theta LFP peaks and their correlation with clinical severity and stimulation site. — Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol
• The study hypothesises that reproducible low-frequency alpha-theta LFP peaks may be biomarkers of dystonia severity, treatment response, and optimal stimulation location. — Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol
• Prior dystonia studies found low-frequency theta-alpha GPi activity associated with dystonia severity and clinical improvement after stimulation. — Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol
• Chronic sensing may provide a clinically relevant signal during real-world stimulation and movement. — Prospective multi-phase observational study evaluating local field potentials to guide deep brain stimulation programming in dystonia at a UK Tertiary Neurosciences Centre (LFP-DYT): a protocol