Low-Grade Albuminuria

Dosage & preparation

Risks & contraindications

Comparisons

Evidence quality

Highlighted claims

• The 2% relative MACE increase per 1 mg/g UACR within the normal range is modest at the individual level but meaningful as a population-level risk gradient. — Relationship between the urinary albumin-to-creatinine ratio and cardiovascular adverse outcomes in the Beijing community population: a prospective cohort study
• The Framingham Heart Study found that low UACR predicted cardiovascular events and all-cause mortality over 6 years in non-diabetic, non-hypertensive participants, independent of traditional risk factors. — Relationship between the urinary albumin-to-creatinine ratio and cardiovascular adverse outcomes in the Beijing community population: a prospective cohort study
• Even within the normal UACR range below 30 mg/g, increasing UACR was significantly associated with higher MACE risk. — Relationship between the urinary albumin-to-creatinine ratio and cardiovascular adverse outcomes in the Beijing community population: a prospective cohort study
• Each 1 mg/g increase in UACR within the normal range corresponded to a 2% increase in MACE risk. — Relationship between the urinary albumin-to-creatinine ratio and cardiovascular adverse outcomes in the Beijing community population: a prospective cohort study
• After full multivariable adjustment, the highest tertile of low-grade albuminuria remained significantly associated with acute myocardial infarction but the finding is considered preliminary pending further validation. — Relationship between the urinary albumin-to-creatinine ratio and cardiovascular adverse outcomes in the Beijing community population: a prospective cohort study