Maternal Lifestyle Factors

Uses

Benefits

Risks & contraindications

Highlighted claims

• MR-PREG aims to improve understanding of how modifiable maternal lifestyle factors affect APPO risk. — Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration – improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes
• Higher maternal BMI increases risk for multiple APPOs including gestational hypertension, pre-eclampsia, gestational diabetes, delivery interventions, LGA, and neonatal intensive care admission. — Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration – improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes
• Maternal smoking was associated with fetal growth restriction from early in the second trimester, while early cessation did not show a major fetal growth deficit. — Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration – improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes
• Higher maternal BMI appeared to reduce the odds of small for gestational age and breastfeeding, with no detectable effect on perinatal depression. — Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration – improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes
• Insomnia may increase perinatal depression risk but showed no apparent effect on most other evaluated APPOs. — Cohort profile: the Mendelian randomisation in pregnancy (MR-PREG) collaboration – improving evidence for prevention and treatment of adverse pregnancy and perinatal outcomes