Microbiota-targeted Therapeutics

Uses

How it works

Evidence quality

Highlighted claims

• Dietary interventions, standalone prebiotics, and probiotics in functional foods are excluded from the review. — Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials
• Eligible microbiota-targeted interventions include probiotics, synbiotics, postbiotics, FMT, live biotherapeutic products, and antibiotics. — Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials
• The review evaluates microbiota-targeted interventions across autoimmune and inflammatory rheumatic diseases because no comprehensive, current review spans all such interventions and diseases. — Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials
• Microbiota-targeted therapies may act through changes in microbial composition and metabolites, gut barrier restoration, and pharmacomicrobiomic effects. — Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials