Mutation Accumulation
Cross-source consensus on Mutation Accumulation from 1 sources and 5 claims.
1 sources · 5 claims
How it works
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Evidence quality
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Highlighted claims
- Classical evolutionary theories predict that early-acting deleterious mutations are efficiently removed while late-acting harmful mutations can accumulate. — An In Silico Model to Simulate the Evolution of Biological Aging
- In sexual populations, strong selection maintains high survival before maturity and high reproductive potential near maturity. — An In Silico Model to Simulate the Evolution of Biological Aging
- Late-life survival and reproduction modules accumulated more deleterious mutations and showed higher genetic variance. — An In Silico Model to Simulate the Evolution of Biological Aging
- Increased late-life variance argues against aging being an adaptive program in this model. — An In Silico Model to Simulate the Evolution of Biological Aging
- The model predicts higher variance for genetic elements affecting late-life survival and reproduction than for those affecting early-life survival and reproduction. — An In Silico Model to Simulate the Evolution of Biological Aging