Omicron Variant

How it works

Risks & contraindications

Comparisons

Evidence quality

Highlighted claims

• CD4 T-cell epitope conservation for naturally infected individuals decreased from 95% to 88% against Omicron. — T-Cell Epitopes and Omicron Variant Recognition
• CD8 T-cell epitope conservation for naturally infected individuals fell from 98% to 95% against Omicron. — T-Cell Epitopes and Omicron Variant Recognition
• CD4 T-cell epitope conservation in vaccinated individuals dropped from 91% to 72% against Omicron. — T-Cell Epitopes and Omicron Variant Recognition
• CD8 T-cell epitope conservation in vaccinated individuals declined from 94% to 86% against Omicron. — T-Cell Epitopes and Omicron Variant Recognition
• The study is based on real-world data from 211,000 SARS-CoV-2 positive tests examining Omicron prevalence. — Pfizer Vaccine Efficacy Against Omicron
• Omicron reinfects previously infected individuals at 2.3 times the rate observed for prior variants. — Omicron Reinfection Patterns in South Africa
• The Pfizer-BioNTech vaccine is 41 times less likely to neutralize Omicron compared to the original ancestral SARS-CoV-2 strain. — Omicron Immune Escape from COVID-19 Vaccines
• The Omicron wave shows a steeper and more rapid rise in cases than any previous COVID-19 wave in South Africa. — Omicron Reinfection Patterns in South Africa
• Omicron demonstrated incomplete immune escape from vaccine-induced immunity, not total escape. — Omicron Immune Escape from COVID-19 Vaccines
• The emergence of the Omicron variant was associated with a significant decline in vaccine protection against infection. — Pfizer Vaccine Efficacy Against Omicron