Outcomes and Evidence Certainty

Evidence quality

Other

Highlighted claims

• Risk of bias will be assessed with the revised Cochrane Risk of Bias tool for randomized trials. — Comparison of the efficacy of non-pharmacological interventions for patients with heart failure with preserved ejection fraction: protocol for a systematic review and network meta-analysis of randomised controlled trials
• Evidence certainty will be evaluated with GRADE across five domains and rated from high to very low. — Comparison of the efficacy of non-pharmacological interventions for patients with heart failure with preserved ejection fraction: protocol for a systematic review and network meta-analysis of randomised controlled trials
• The detailed methods define primary outcomes as exercise capacity and health-related quality of life. — Comparison of the efficacy of non-pharmacological interventions for patients with heart failure with preserved ejection fraction: protocol for a systematic review and network meta-analysis of randomised controlled trials
• Secondary outcomes include natriuretic peptide biomarkers and cardiac function measures. — Comparison of the efficacy of non-pharmacological interventions for patients with heart failure with preserved ejection fraction: protocol for a systematic review and network meta-analysis of randomised controlled trials
• Network meta-analysis evidence will also be assessed with CINeMA separately for lifestyle or behavioural and device-based interventions. — Comparison of the efficacy of non-pharmacological interventions for patients with heart failure with preserved ejection fraction: protocol for a systematic review and network meta-analysis of randomised controlled trials