OVRV1

Uses

How it works

Comparisons

Background

Where it comes from

Highlighted claims

• The study will assess whether OVRV1, if detected in CSF, can infect neural cells and exhibit neurotropism or neurotoxicity. — Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study in Aketi, Democratic Republic of the Congo
• Viral metagenomics and transcriptome analysis identified two potential pathogenic rhabdoviruses in O. volvulus: OVRV1 and OVRV2. — Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study in Aketi, Democratic Republic of the Congo
• OVRV1 has been detected in most tested adult O. volvulus worms, microfilariae, and larvae. — Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study in Aketi, Democratic Republic of the Congo
• OVRV2 was detected only in the L2 larval stage, which is not transmitted to humans, making its relevance to human disease negligible. — Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study in Aketi, Democratic Republic of the Congo
• OVRV1 is hypothesised to play a role in OAE pathogenesis. — Exploring potential pathogenesis mechanisms of onchocerciasis-associated epilepsy through cerebrospinal fluid analysis of children with complex febrile seizures: a pilot study in Aketi, Democratic Republic of the Congo