Paediatric Medicines
Cross-source consensus on Paediatric Medicines from 1 sources and 5 claims.
1 sources · 5 claims
Dosage & preparation
Risks & contraindications
Background
Highlighted claims
- Children's dosing is often extrapolated from adult studies and adjusted for body weight. — Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries
- Adult-to-child dose extrapolation can be inadequate because children and adults may respond differently even after weight adjustment. — Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries
- Paediatric populations require granular dosing and formulations tailored to developmental and clinical differences. — Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries
- Crushing tablets for infants and small children can reduce tolerability and risk subtherapeutic dosing. — Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries
- Paediatric formulations can be delayed long after adult medicines are available. — Individual patient data meta-analysis: a cost-effective and efficient tool to advance paediatric research in low- and middle-income countries