Paediatric Procedural Sedation

Uses

Preparation

Risks & contraindications

Highlighted claims

• Children with haematologic malignancies require repeated invasive diagnostic and treatment procedures, primarily bone marrow aspirates and lumbar punctures. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Children are required to fast for 8 hours before each procedure and receive no premedication. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• A trained nurse provides age-appropriate psychological preparation, including therapeutic play and distraction, before each procedure. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Children under 6 years are excluded from the trial because validated observational tools for assessing psychotomimetic profiles in pre-verbal children are not yet available. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol
• Fear and distressed behaviour are reported in 17–27% of children with leukaemia undergoing repeated deep sedation. — Safety and efficacy of esketamine versus remifentanil as adjuncts to propofol sedation in children undergoing haematologic-oncologic procedures in China: a single-centre, randomised, controlled, crossover trial protocol