Problematic Evidence

Cross-source consensus on Problematic Evidence from 1 sources and 5 claims.

1 sources · 5 claims

How it works

The protocol defines problematic evidence as retracted clinical trials and meta-analyses that included retracted trials. — Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol
Fraudulent or unreliable trials can contaminate evidence syntheses and influence guideline recommendations. — Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol
Limiting the study to retracted trials and reviews that included them is expected to underestimate the true impact. — Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol
The study assumes all retracted trials are fraudulent as a pragmatic choice, even though not all retractions are due to fraud. — Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol
Retracted trials are treated as only a visible subset of all problematic trials. — Investigating the impact of problematic evidence on clinical practice guidelines and associated patient outcomes (VITALITY Study II): protocol