Protein-Coding Genes

How it works

Comparisons

Evidence quality

Highlighted claims

• Across the main dataset, absolute protein-coding length was not significantly correlated with lifespan. — Noncoding RNAs evolutionarily extend animal lifespan
• The article says humans and mice share more than 80% of orthologous protein-coding genes despite large lifespan differences. — Noncoding RNAs evolutionarily extend animal lifespan
• Relative protein-coding length was negatively associated with lifespan. — Noncoding RNAs evolutionarily extend animal lifespan
• The paper interprets protein-coding content as insufficient to explain lifespan extension. — Noncoding RNAs evolutionarily extend animal lifespan
• The proposed mechanism argues that protein synthesis and protein function are more energy-consuming than ncRNA-based regulation. — Noncoding RNAs evolutionarily extend animal lifespan