Randomisation and Blinding

Cross-source consensus on Randomisation and Blinding from 2 sources and 11 claims.

2 sources · 11 claims

Preparation

Other

Highlighted claims

The design is double-blind for patients and study physicians. — Study protocol for testing pharmacological conditioning as a drug dose reduction strategy in patients with psoriasis in a randomised controlled trial
Allocation is concealed using sequentially numbered opaque sealed envelopes. — Efficacy of periodontal therapy in preventing tooth loss and improving masticatory function in patients with chronic kidney disease: a protocol for a single-centre randomised controlled trial in China
Randomisation occurs after enrolment and written consent and is stratified by PASI severity. — Study protocol for testing pharmacological conditioning as a drug dose reduction strategy in patients with psoriasis in a randomised controlled trial
An independent statistician generates the allocation sequence and does not participate in assessments or interventions. — Efficacy of periodontal therapy in preventing tooth loss and improving masticatory function in patients with chronic kidney disease: a protocol for a single-centre randomised controlled trial in China
Patients wear a sleep mask during injections so they cannot see the medication. — Study protocol for testing pharmacological conditioning as a drug dose reduction strategy in patients with psoriasis in a randomised controlled trial
Block randomisation with variable block sizes is used to balance groups and minimise allocation bias. — Efficacy of periodontal therapy in preventing tooth loss and improving masticatory function in patients with chronic kidney disease: a protocol for a single-centre randomised controlled trial in China
Outcome assessors are blinded and do not have access to treatment records. — Efficacy of periodontal therapy in preventing tooth loss and improving masticatory function in patients with chronic kidney disease: a protocol for a single-centre randomised controlled trial in China
A postdoctoral researcher outside care, recruitment, and data collection generates the randomisation schedule. — Study protocol for testing pharmacological conditioning as a drug dose reduction strategy in patients with psoriasis in a randomised controlled trial
Participants and treating investigators cannot be blinded because periodontal treatment makes blinding impractical. — Efficacy of periodontal therapy in preventing tooth loss and improving masticatory function in patients with chronic kidney disease: a protocol for a single-centre randomised controlled trial in China
Research assistants manage blinding, medication or placebo administration, and beverage delivery. — Study protocol for testing pharmacological conditioning as a drug dose reduction strategy in patients with psoriasis in a randomised controlled trial