Randomisation and Statistical Analysis

Cross-source consensus on Randomisation and Statistical Analysis from 1 sources and 5 claims.

1 sources · 5 claims

Evidence quality

Allocation concealment uses sealed, opaque, sequentially numbered envelopes. — LED red light for atrophy and microcirculation in pathologic myopia (RAMP): study design and protocol for a multicentre randomised controlled trial
The target sample size is 158 participants after allowing for 20% dropout. — LED red light for atrophy and microcirculation in pathologic myopia (RAMP): study design and protocol for a multicentre randomised controlled trial
Primary efficacy analysis follows intention-to-treat, with per-protocol analysis used for robustness. — LED red light for atrophy and microcirculation in pathologic myopia (RAMP): study design and protocol for a multicentre randomised controlled trial
A blinded statistician generates the 1:1 randomisation sequence using SAS 9.4. — LED red light for atrophy and microcirculation in pathologic myopia (RAMP): study design and protocol for a multicentre randomised controlled trial
Clinical examiners, ophthalmologists, and statisticians remain blinded throughout the study. — LED red light for atrophy and microcirculation in pathologic myopia (RAMP): study design and protocol for a multicentre randomised controlled trial