Renal Mechanisms
Cross-source consensus on Renal Mechanisms from 1 sources and 5 claims.
1 sources · 5 claims
How it works
Highlighted claims
- PPAR-gamma is expressed in the renal cortex and medulla and participates in metabolic processes. — Lobeglitazone and the risk of renal progression in Korean patients with type 2 diabetes mellitus: a retrospective cohort study
- Under hyperglycaemia, impaired SGLT-mediated glucose transport in the proximal convoluted tubule can promote epithelial-mesenchymal transition and renal fibrosis. — Lobeglitazone and the risk of renal progression in Korean patients with type 2 diabetes mellitus: a retrospective cohort study
- Animal evidence suggests lobeglitazone can suppress extracellular matrix production by inhibiting TGF-beta/Smad3 signalling. — Lobeglitazone and the risk of renal progression in Korean patients with type 2 diabetes mellitus: a retrospective cohort study
- PPAR-gamma agonists have been reported to reverse high-glucose-induced epithelial-mesenchymal transition through PI3K/Akt, GSK beta, Snail 1, and beta-catenin pathways. — Lobeglitazone and the risk of renal progression in Korean patients with type 2 diabetes mellitus: a retrospective cohort study
- Lobeglitazone downregulated fibrosis-related genes in animal evidence. — Lobeglitazone and the risk of renal progression in Korean patients with type 2 diabetes mellitus: a retrospective cohort study