Review Strengths and Limitations

Evidence quality

Highlighted claims

• The protocol identifies PRISMA-P adherence, multi-database searching, dual-reviewer screening, independent arbitration, risk-of-bias tools, and GRADE as strengths. — Offloading orthotic insoles on healing of diabetic foot ulcers: a protocol for systematic review and meta-analysis
• The review anticipates variability in study design, insole material and construction, and outcome measurement instruments. — Offloading orthotic insoles on healing of diabetic foot ulcers: a protocol for systematic review and meta-analysis
• The review anticipates that high-quality RCT evidence on insoles for active-ulcer healing may be limited. — Offloading orthotic insoles on healing of diabetic foot ulcers: a protocol for systematic review and meta-analysis
• The review recognizes a risk of publication bias favoring positive results. — Offloading orthotic insoles on healing of diabetic foot ulcers: a protocol for systematic review and meta-analysis