SIGNAL Registry

Uses

Risks & contraindications

Background

Highlighted claims

• The SIGNAL registry was established in 2017 at University College London Hospitals NHS Foundation Trust to address gaps in existing stroke registries. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• SIGNAL is a prospective, hospital-based, observational registry enrolling consecutive stroke admissions to the UCLH Comprehensive Stroke Service. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• SIGNAL enrolment was halted in January 2020 due to funding expiry and the COVID-19 pandemic. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• The SIGNAL catchment area covers approximately 1.6 million residents across five North Central London boroughs. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• As a single-centre, single-city registry, SIGNAL's findings may not generalise to rural, non-metropolitan, or non-NHS healthcare settings. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• Anonymised SIGNAL data may be requested by external researchers subject to Steering Committee review and a formal data-sharing agreement. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry
• A 10-year follow-up phase is planned as a formal research study, distinct from the clinical registry. — Stroke Investigation Group in North and Central London (SIGNAL): cohort profile of a prospective large-scale comprehensive stroke registry