Study Design and Analysis

Cross-source consensus on Study Design and Analysis from 1 sources and 6 claims.

1 sources · 6 claims

Risks & contraindications

The target cohort includes 850 children, evenly divided between HIV-exposed uninfected and HIV-unexposed uninfected groups. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project
Evaluators will be blinded to participant group status to reduce diagnostic bias. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project
Binary logistic regression will test whether HIV and antiretroviral exposure is associated with categorical autism outcome. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project
Lasso logistic regression will be used to select the combination of eye-tracking markers that best predicts autism. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project
The Alama Project consists of one study visit lasting about two to four hours. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project
Power calculations assume a conservative 20% recruitment attrition rate from the final Tabiri sample completing 24-month visits. — Autism outcomes and neurobehavioural markers in young children born to mothers with HIV in Kenya: a protocol for the Alama project