Study Procedures

Cross-source consensus on Study Procedures from 1 sources and 6 claims.

1 sources · 6 claims

Other

Highlighted claims

The primary endpoint is percentage change in body weight at weeks 12 and 24. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study
Eligible participants are adults at least 18 years old with BMI at least 24 kg/m² who plan to start NuSH-based therapy and can comply with follow-up. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study
Data collection occurs at baseline, week 4, week 12, week 24, and annually for up to 5 years. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study
Adverse events will be systematically recorded with characteristics, severity, timing, outcome, and possible treatment causality. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study
Repeated outcomes will be analysed using longitudinal mixed-effects models, with regression adjustment for clinically relevant confounders. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study
Secondary endpoints include weight response thresholds, glucose and lipid metabolism, MRI liver and pancreatic fat, adverse events, safety labs, and thyroid ultrasonography. — Hongkou Advanced Research on Metabolism and Obesity iNtervention studY (HARMONY): a protocol for a longitudinal cohort study