Surgical Glove Compression Therapy

Uses

Benefits

Dosage & preparation

Evidence quality

Highlighted claims

• The intervention requires wearing two layers of tight-fitting surgical gloves, one size smaller than normal fit, from 30 minutes before to 30 minutes after oxaliplatin infusion. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial
• Surgical gloves are inexpensive, widely available, technically simple, and already used clinically for infection prevention. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial
• Zhang et al reported reduced neuropathy with compression in oxaliplatin-treated patients, but the study was limited by a single-centre design, a small sample of 60 patients, and no long-term follow-up. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial
• Surgical glove compression therapy is being studied for OIPN because peripheral circulation suppression has shown promise for preventing paclitaxel-induced peripheral neuropathy. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial
• A double-blind glove trial by Kotani et al found no preventive effect, but its validity was undermined because participants could distinguish tight from normal-sized gloves. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial
• Prior studies reported that wearing surgical gloves reduced grade 2 or higher neuropathy during nab-paclitaxel treatment. — Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial–the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial