Systematic Review and Meta-Analysis

Uses

How it works

Preparation

Evidence quality

Where it comes from

Highlighted claims

• The first study phase will identify and quantify predictors of CRT response through systematic review and meta-analysis. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol
• Two investigators will independently screen studies to support objectivity and reproducibility. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol
• Cohort quality will be assessed with the Newcastle-Ottawa Scale and classified as high, moderate, or low. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol
• Pooled estimates will be generated with DerSimonian-Laird random-effects models using generic inverse-variance weighting. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol
• The review will search English- and Chinese-language databases from inception to January 31, 2026. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol
• Eligible studies must include patients meeting established CRT implantation criteria and report extractable baseline predictor estimates for CRT outcomes. — Development and real-world cohort validation of a meta-analysis-derived simplified scoring model for cardiac resynchronisation therapy response: a study protocol