Teratogenic Mechanisms
Cross-source consensus on Teratogenic Mechanisms from 1 sources and 4 claims.
1 sources · 4 claims
How it works
Risks & contraindications
Background
Highlighted claims
- Pesticides can interfere with normal organogenesis through four mechanistic pathways. — Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol
- The identified pathways include preconception DNA damage, postconception structural disruption, endocrine interference, and epigenetic action. — Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol
- The first trimester is presented as a heightened susceptibility window because organogenesis is active and embryos have limited detoxification capacity. — Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol
- Nitrofen is used as a historical example showing that a specific pesticide can reliably cause a specific structural anomaly in animal models. — Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol